Undifferentiated carcinoma of the pancreas with osteoclast like giant cells: Literature review with CT/MR imaging findings in 3 cases

Kun Zhan; Shizheng Zhang; Peng Hu; Jiao Chen; Wangwang Liu; Zhongfeng Niu

doi:10.1016/j.radcr.2022.03.032

Undifferentiated carcinoma of the pancreas with osteoclast like giant cells: Literature review with CT/MR imaging findings in 3 cases

Radiol Case Rep. 2022 May 13;17(7):2529-2533. doi: 10.1016/j.radcr.2022.03.032. eCollection 2022 Jul.

Authors

Kun Zhan¹, Shizheng Zhang¹, Peng Hu¹, Jiao Chen¹, Wangwang Liu², Zhongfeng Niu¹

Affiliations

¹ Department of Radiology, Sir Run Run Shaw hospital, Zhejiang University School of Medicine, Hangzhou City 310016, Zhejiang Province, China.
² Department of Pathology, Sir Run Run Shaw hospital, Zhejiang University School of Medicine, Hangzhou City 310016, Zhejiang Province, China.

Abstract

Undifferentiated carcinoma with osteoclast-like giant cells of pancreas (UCOGCP) is a relatively rare tumor worldwide. Its accurate preoperative diagnosis is extremely difficult. Because the mass is usually large and closely related to neighboring structures, it is difficult to locate the tumor and it is often misdiagnosed as pancreatic cancer, neuroendocrine tumor or gastrointestinal stromal tumor. Combining literature to analyze UCOGCP clinical features (including age of onset, prevalent location) and imaging features (including lesion size, mass nature), to explore the value of preoperative CT and MRI in the diagnosis and differential diagnosis of UCOGCP and hope to help clinical diagnosis and treatment.

Keywords: CT, computed tomography; Computed tomography; DWI, diffusion-weighted imaging; MRI, magnetic resonance imaging; Magnetic resonance imaging; Osteoclast-like giant cell; Pancreas; Pleomorphic giant cell carcinoma; T1WI, T1-weighted image; T2WI, T2-weighted image; UCOGCP, Undifferentiated carcinoma with osteoclast-like giant cell of pancreas; Undifferentiated cancer.

Publication types

Case Reports