Peer support in patients with hematologic malignancies: a systematic review

Bone Marrow Transplant. 2022 Aug;57(8):1240-1249. doi: 10.1038/s41409-022-01709-3. Epub 2022 May 21.

Abstract

Background: Peer support has been utilized and associated with clinical outcomes (e.g., improved mood) in patients with solid malignancies. However, to date, there is minimal literature examining peer support among patients with hematologic malignancies and/or patients who have undergone hematopoietic stem cell transplantation (HSCT).

Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, we completed a systematic review using five databases to assess the relationship between peer support and clinical outcomes (e.g., distress, physical symptoms) among patients with hematologic malignancies or HSCT recipients.

Results: The eight included studies examined peer support in a total of 574 patients. Four intervention studies highlighted the potential benefits of peer support, such as improved physical symptoms. Two studies, one interventional and one cross-sectional, highlighted the need for more empirically based peer support interventions in the HSCT population.

Conclusion: Among patients with hematologic malignancies and/or HSCT recipients, there is a dearth of literature examining the association between peer support and outcomes, although few studies have described a positive association between peer support and better health outcomes. More randomized controlled studies are needed to better understand the role of peer support and peer support interventions on outcomes in these vulnerable populations.

Keywords: Blood Cancers; Bone Marrow Transplantation; Hematologic Malignancies; Hematopoietic Stem Cell Transplantation; Patient-Reported Outcomes; Peer Support; Social Support; Social Wellbeing.

Publication types

  • Review
  • Systematic Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Cross-Sectional Studies
  • Hematologic Neoplasms* / therapy
  • Hematopoietic Stem Cell Transplantation* / adverse effects
  • Humans