Oral submucous fibrosis induced by graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Binjie Liu; Jingwen Cai; Wenjie Li; Gui Liu; Jun Chen

doi:10.1016/j.oraloncology.2022.105919

Oral submucous fibrosis induced by graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Oral Oncol. 2022 Jul:130:105919. doi: 10.1016/j.oraloncology.2022.105919. Epub 2022 May 17.

Authors

Binjie Liu¹, Jingwen Cai¹, Wenjie Li², Gui Liu¹, Jun Chen³

Affiliations

¹ Department of Periodontics and Oral Medicine, Xiangya Stomatological Hospital & Xiangya School of Stomatology, Central South University & Hunan Key Laboratory of Oral Health Research & Hunan Clinical Research Center of Oral Major Diseases and Oral Health & Academician Workstation for Oral-maxillofacial and Regenerative Medicine, Changsha 410008, China.
² Department of Periodontics and Oral Medicine, Xiangya Stomatological Hospital & Xiangya School of Stomatology, Central South University & Hunan Key Laboratory of Oral Health Research & Hunan Clinical Research Center of Oral Major Diseases and Oral Health & Academician Workstation for Oral-maxillofacial and Regenerative Medicine, Changsha 410008, China; Department of Oral Health Science, School of Dentistry, University of Washington, Seattle, WA 98195, USA.
³ Department of Periodontics and Oral Medicine, Xiangya Stomatological Hospital & Xiangya School of Stomatology, Central South University & Hunan Key Laboratory of Oral Health Research & Hunan Clinical Research Center of Oral Major Diseases and Oral Health & Academician Workstation for Oral-maxillofacial and Regenerative Medicine, Changsha 410008, China. Electronic address: chenjun1222@csu.edu.cn.

PMID: 35594775
DOI: 10.1016/j.oraloncology.2022.105919

Abstract

Graft-versus-host disease (GVHD) is one of the most common and serious complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT). About 45%∼83% of patients develop GVHD in the oral cavity. There has no medical records of oral submucous fibrosis (OSF) induced by GVHD after allo-HSCT, which should be brought to the attention of dentists.

Keywords: Allogeneic hematopoietic stem cell transplantation (allo-HSCT); Graft-versus-host disease (GVHD); Oral submucous fibrosis (OSF).

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Graft vs Host Disease* / etiology
Hematopoietic Stem Cell Transplantation* / adverse effects
Humans
Oral Submucous Fibrosis* / etiology
Transplantation, Homologous / adverse effects