Remote Programming in Patients With Parkinson's Disease After Deep Brain Stimulation: Safe, Effective, and Economical

Pan Nie; Jibo Zhang; Xin Yang; Yuyang Shao; Xiuming Zhang; Wen Liu; Kai Fu; Jincao Chen; Jie Zhang

doi:10.3389/fneur.2022.879250

Remote Programming in Patients With Parkinson's Disease After Deep Brain Stimulation: Safe, Effective, and Economical

Front Neurol. 2022 May 3:13:879250. doi: 10.3389/fneur.2022.879250. eCollection 2022.

Authors

Pan Nie^{1

2}, Jibo Zhang^{1

2}, Xin Yang^{1

2}, Yuyang Shao^{1

2}, Xiuming Zhang^{1

2}, Wen Liu^{1

2}, Kai Fu^{1

2}, Jincao Chen¹, Jie Zhang^{1

2}

Affiliations

¹ Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
² Center for Functional Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, China.

Abstract

Objective: The purpose of this study was to evaluate the safety, efficiency, and cost expenditure of remote programming in patients with Parkinson's disease (PD) after deep brain stimulation (DBS).

Methods: A total of 74 patients who underwent DBS at the Department of Neurosurgery, Zhongnan Hospital of Wuhan University between June 2018 and June 2020 were enrolled in this study. There were 27 patients in the remote programming group and 47 patients in the outpatient programming group. Clinical data, programming efficiency, adverse events, expenditure, and satisfaction were compared between the two groups.

Results: A total of 36 times of remote programming were performed on the 27 patients in the remote programming group, and four had mild adverse events during programming, and the adverse events disappeared within 1 week. The satisfaction questionnaire showed that 97.3% of the patients were satisfied with the surgical effect. The patients in the remote programming group (88.9%) were more likely to receive long-term programming after DBS than the patients in the outpatient programming group (74.5%). The Parkinsonism symptoms improved in both programming groups. The majority (18/27) of patients in the remote programming group lived away from the programming center, while the majority (27/47) of patients in the outpatient programming group lived in Wuhan, where the programming center was located (P = 0.046). The cost per patient per programming was US$ 43.5 in the remote programming group and $59.5 (56-82.7) in the outpatient programming group (P < 0.001). The median time cost for each visit was 30 min (25-30) in the remote programming group and 150 min (135-270.0) in the outpatient programming group (P < 0.001).

Conclusion: Remote programming is safe and effective after DBS in patients with Parkinson's disease. Moreover, it reduces expenditure and time costs for patients and achieves high satisfaction, particularly for patients living far from programming centers.

Keywords: Parkinson's disease; cost; deep brain stimulation; equipment safety; remote programming; telemedicine.