Poststreptococcal Myalgia and Protracted Febrile Myalgia Syndrome: Similar Yet Different

J Pediatr. 2022 Aug:247:163-167.e2. doi: 10.1016/j.jpeds.2022.02.057. Epub 2022 May 17.

Abstract

We compare cases of familial Mediterranean fever-related protracted febrile myalgia and poststreptococcal myalgia, both rare disorders presenting with fever, myalgia, and inflammatory biomarkers. Although clinical symptoms may be undistinguishable, steroids are usually required in protracted febrile myalgia syndrome and poststreptococcal myalgia most often respond to nonsteroidal anti-inflammatory drugs. Awareness of poststreptococcal myalgia and preceding history may prevent unnecessary tests or overtreatment.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Familial Mediterranean Fever* / complications
  • Familial Mediterranean Fever* / diagnosis
  • Familial Mediterranean Fever* / drug therapy
  • Fever / diagnosis
  • Fever / drug therapy
  • Fever / etiology
  • Humans
  • Myalgia* / diagnosis
  • Myalgia* / etiology
  • Overtreatment

Substances

  • Anti-Inflammatory Agents, Non-Steroidal