Tensor Gradient L₀-Norm Minimization-Based Low-Dose CT and Its Application to COVID-19

IEEE Trans Instrum Meas. 2021 Jan 19:70:4503012. doi: 10.1109/TIM.2021.3050190. eCollection 2021.

Abstract

Methods to recover high-quality computed tomography (CT) images in low-dose cases will be of great benefit. To reach this goal, sparse-data subsampling is one of the common strategies to reduce radiation dose, which is attracting interest among the researchers in the CT community. Since analytic image reconstruction algorithms may lead to severe image artifacts, the iterative algorithms have been developed for reconstructing images from sparsely sampled projection data. In this study, we first develop a tensor gradient L0-norm minimization (TGLM) for low-dose CT imaging. Then, the TGLM model is optimized by using the split-Bregman method. The Coronavirus Disease 2019 (COVID-19) has been sweeping the globe, and CT imaging has been deployed for detection and assessing the severity of the disease. Finally, we first apply our proposed TGLM method for COVID-19 to achieve low-dose scan by incorporating the 3-D spatial information. Two COVID-19 patients (64 years old female and 56 years old man) were scanned by the [Formula: see text]CT 528 system, and the acquired projections were retrieved to validate and evaluate the performance of the TGLM.

Keywords: Chest CT; Coronavirus Disease 2019 (COVID-19); low-dose computed tomography (CT); tensor gradient L₀-norm.

Grants and funding

This work was supported in part by the Li Ka Shing Foundation and in part by the National Natural Science Foundation of China under Grant 61801336.