Recommendations of the Spanish Group on Crohn's Disease and Ulcerative Colitis on the importance, screening and vaccination in inflammatory bowel disease patients

Gastroenterol Hepatol. 2022 Dec;45(10):805-818. doi: 10.1016/j.gastrohep.2022.03.012. Epub 2022 May 14.
[Article in English, Spanish]

Abstract

Patients with inflammatory bowel disease (IBD) may require different immunosuppressive treatments throughout their illness. It is essential to assess the immunization status of patients at diagnosis or, if this is not possible, at least before the beginning of immunosuppressive therapy and, subsequently, administering the appropriate vaccines. Therefore, the aim of this work is to establish clear and concise recommendations on vaccination in patients with IBD in the different settings of our clinical practice including vaccination in children, during pregnancy, breastfeeding or on trips. This consensus document emphasises the differences between inactivated and attenuated vaccines and the different degrees of immunosuppression and correlates them with the administration of both mandatory and optional vaccines recommended to our patients with IBD. Finally, as a summary, 17 recommendations are established based on the available scientific evidence and expert opinion. A multidisciplinary team with extensive experience in IBD and vaccination, made up of specialists in gastroenterology, paediatrics, nursing and pharmacy, has participated in the preparation of these recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis.

Keywords: Cribado; Enfermedad inflamatoria intestinal; Infección; Infection; Inflammatory bowel disease; Prevención; Prevention; Screening; Vaccination; Vacuna.

Publication types

  • Practice Guideline

MeSH terms

  • Child
  • Chronic Disease
  • Colitis, Ulcerative* / drug therapy
  • Crohn Disease* / drug therapy
  • Female
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Inflammatory Bowel Diseases* / drug therapy
  • Pregnancy
  • Vaccination

Substances

  • Immunosuppressive Agents