An unconventional vertical fluidic-controlled wearable platform for synchronously detecting sweat rate and electrolyte concentration

Biosens Bioelectron. 2022 Aug 15:210:114351. doi: 10.1016/j.bios.2022.114351. Epub 2022 May 10.

Abstract

Epidermal microfluidic devices with long microchannels have been developed for continuous sweat analysis, which are crucial to assess personal hydration status and underlying health conditions. However, the flow resistance in long channels and the ionic concentration variation significantly affect the accuracy of both the sweat rate and electrolyte concentration measurements. Herein, we present a novel fluidic-controlled wearable platform for synchronously dropwise-detecting the sweat rate and total electrolyte concentration. The unconventional platform consisting of a vertically shortened channel, a pair of embedded electrodes and an absorption layer, is designed to minimize the flow resistance and transform sweat fluidics into uniform micro-droplets for chronological and dropwise detection. Real-time sweat conductance is decoupled from a square-wave-like curve, where the sweat rate and electrolyte concentration can be derived from the interval time and peak value, respectively. Flexible and wearable band devices are demonstrated to show their potential application for hydration status assessment during exercises.

Keywords: Epidermal microfluidic devices; Sweat analysis; Sweat conductance; Sweat rates; Wearable sweat sensors.

MeSH terms

  • Biosensing Techniques*
  • Electrolytes
  • Lab-On-A-Chip Devices
  • Sweat
  • Wearable Electronic Devices*

Substances

  • Electrolytes