RETRACTED: Comparison between diagnostic performance of intestinal Fusobacterium nucleatum, Bacteroides fragilis and Escherichia coli in 5-fluorouracil resistance to colorectal cancer: A meta‑analysis

Cancer Treat Res Commun. 2022:32:100536. doi: 10.1016/j.ctarc.2022.100536. Epub 2022 Feb 22.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors, as the current findings are incomplete and need to be validated. The reasons include that the results are not comparable to the diagnostic performance of three bacteria species in 5-fluorouracil resistance in CRC from the clinical studies which are conducted to detect each type of bacteria separately. Additional results of quantifying three bacteria species in the same colorectal cancer group are required to validate the conclusion.

Keywords: 5-Fluorouracil (5-FU) resistance; Bacteroides fragilis (B. fragilis); Colorectal cancer (CRC); Escherichia coli (E. coli); Fusobacterium nucleatum (F. nucleatum, Fn).

Publication types

  • Meta-Analysis
  • Review
  • Research Support, Non-U.S. Gov't
  • Retracted Publication

MeSH terms

  • Bacteroides fragilis
  • Colorectal Neoplasms* / diagnosis
  • Colorectal Neoplasms* / drug therapy
  • Escherichia coli
  • Fluorouracil / pharmacology
  • Fluorouracil / therapeutic use
  • Fusobacterium nucleatum*
  • Humans

Substances

  • Fluorouracil