The Lactoferrin Phenomenon-A Miracle Molecule

Molecules. 2022 May 4;27(9):2941. doi: 10.3390/molecules27092941.

Abstract

Numerous harmful factors that affect the human body from birth to old age cause many disturbances, e.g., in the structure of the genome, inducing cell apoptosis and their degeneration, which leads to the development of many diseases, including cancer. Among the factors leading to pathological processes, microbes, viruses, gene dysregulation and immune system disorders have been described. The function of a protective agent may be played by lactoferrin as a "miracle molecule", an endogenous protein with a number of favorable antimicrobial, antiviral, antioxidant, immunostimulatory and binding DNA properties. The purpose of this article is to present the broad spectrum of properties and the role that lactoferrin plays in protecting human cells at all stages of life.

Keywords: aging; cancer; immunomodulation; lactoferrin; oxidative stress.

Publication types

  • Review

MeSH terms

  • Humans
  • Immune System / metabolism
  • Lactoferrin / chemistry
  • Lactoferrin / genetics
  • Lactoferrin / metabolism*
  • Viruses* / metabolism

Substances

  • LTF protein, human
  • Lactoferrin

Grants and funding

This research was funded by Medical University of Białystok, Poland. no.: SUB/2/DN/22/001/2201.