1 Yu-Sheng Chang, MD, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Shuang Ho Hospital, New Taipei City, Taiwan; Yu-Chuan Shen, MD, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Jin-Hua Chen, PhD, Biostatistics Center, College of Management, Taipei Medical University, Taipei, Taiwan, Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei, Taiwan; and Chi-Ching Chang, PhD, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.