Change of Left Ventricular Geometric Pattern in Patients with Preserved Ejection Fraction Undergoing Coronary Artery Bypass Grafting

J Cardiovasc Transl Res. 2022 Dec;15(6):1444-1454. doi: 10.1007/s12265-022-10249-6. Epub 2022 May 11.

Abstract

Left ventricular (LV) remodeling and geometric patterns are associated with variations in prognosis. Two hundred twenty-eight patients who underwent selective isolated coronary artery bypass grafting (CABG) were included, divided into normal geometry, concentric remodeling, concentric hypertrophy, and eccentric hypertrophy at baseline. More than half participants with normal geometry at baseline remained in that category, and similar ratio of concentric remodeling reverted to normal geometry on follow-up. The concentric hypertrophy at baseline tended to progress to eccentric geometry rather than normal geometry, while changes from eccentric to concentric hypertrophy was uncommon. iLVEDD had a significant association with an increased risk of developing an abnormal geometric pattern from a normal or concentric remodeling pattern, and iLVESD and LAScd involved in the regression from an abnormal geometric pattern. Thus, dynamic changes in LV geometric pattern are common on 1-year follow-up after CABG and LA strain has an incremental role for early detection in this process.

Keywords: CABG; Echocardiography; Left ventricular geometry; Strain measurements.

MeSH terms

  • Coronary Artery Bypass / adverse effects
  • Echocardiography
  • Heart Ventricles / diagnostic imaging
  • Humans
  • Hypertension*
  • Hypertrophy, Left Ventricular* / diagnostic imaging
  • Hypertrophy, Left Ventricular* / etiology
  • Stroke Volume
  • Ventricular Function, Left
  • Ventricular Remodeling