Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study

Gut. 2023 Mar;72(3):604-606. doi: 10.1136/gutjnl-2021-326299. Epub 2022 May 10.

Amée M Buziau^{1

2

3}, Philip J Law⁴, Gabriella Blokland⁵, Casper Schalkwijk^{2

3}, Jean Scheijen^{2

3}, Pomme Simons^{1

2

3}, Carla van der Kallen^{2

6}, Simone Eussen^{2

7

8}, Pieter C Dagnelie^{2

6}, Marleen van Greevenbroek^{2

3}, Richard S Houlston⁴, Anke Wesselius^{9

10}, Molly Went⁴, Coen Stehouwer^{2

6}, Martijn Cgj Brouwers^{11

2}

¹ Department of Internal Medicine, division of Endocrinology and Metabolic Disease, Maastricht University Medical Centre, Maastricht, The Netherlands.
² CARIM School for Cardiovascular disease, Maastricht University, Maastricht, The Netherlands.
³ Department of Internal Medicine, Division of General Internal Medicine, Laboratory for Metabolism and Vascular Medicine, Maastricht University, Maastricht, The Netherlands.
⁴ Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK.
⁵ Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.
⁶ Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
⁷ Department of Epidemiology, Maastricht University, Maastricht, The Netherlands.
⁸ CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
⁹ NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
¹⁰ Department of Complex Genetics and Epidemiology, Maastricht University, Maastricht, The Netherlands.
¹¹ Department of Internal Medicine, division of Endocrinology and Metabolic Disease, Maastricht University Medical Centre, Maastricht, The Netherlands mcgj.brouwers@mumc.nl.

No abstract available

Keywords: COLORECTAL CANCER; GENETIC POLYMORPHISMS; NUTRITION.

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