Evidence of Transmission and Circulation of Deltacron XD Recombinant Severe Acute Respiratory Syndrome Coronavirus 2 in Northwest France

Alice Moisan; Brice Mastrovito; Fabienne De Oliveira; Mélanie Martel; Hugues Hedin; Marie Leoz; Nicolas Nesi; Justine Schaeffer; Meriadeg Ar Gouilh; Jean-Christophe Plantier

doi:10.1093/cid/ciac360

Evidence of Transmission and Circulation of Deltacron XD Recombinant Severe Acute Respiratory Syndrome Coronavirus 2 in Northwest France

Clin Infect Dis. 2022 Nov 14;75(10):1841-1844. doi: 10.1093/cid/ciac360.

Affiliations

¹ Laboratory of Virology, Normandie University, Université de Rouen Normandie, Université de Caen Normandie, Inserm Unité Mixte de Recherche 1311 Dynamique Microbienne associée aux infections Urinaires et Respiratoires, Centre Hospitalier Universitaire Rouen, Rouen, France.
² Regional Office, Santé publique France, Rouen, France.
³ Normandie University, Université de Rouen Normandie, Université de Caen Normandie, Inserm Unité Mixte de Recherche 1311 Dynamique Microbienne associée aux infections Urinaires et Respiratoires, Rouen, France.
⁴ Department of Virology, Normandie University, Université de Caen Normandie, Université de Rouen Normandie, Inserm Unité Mixte de Recherche 1311 Dynamique Microbienne associée aux infections Urinaires et Respiratoires, Centre Hospitalier Universitaire Caen Normandie, Caen, France.
⁵ Infectious Diseases Division, Santé publique France, Saint-Maurice, France.

Abstract

In February 2022, samples collected in northwest France showed discordant molecular results. After virological and epidemiological investigations, 17 cases of Deltacron XD recombinant severe acute respiratory syndrome coronavirus 2 were confirmed by sequencing or suspected due to epidemiological links, showing evidence of an extended transmission event and circulation of this form, with low clinical severity.

Keywords: Deltacron; SARS-CoV-2; chain of transmission; recombination; variants.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

COVID-19*
France / epidemiology
Humans
SARS-CoV-2* / genetics