Outcomes of Late-Preterm and Term Infants Born to SARS-CoV-2-Positive Mothers

J Korean Med Sci. 2022 May 9;37(18):e147. doi: 10.3346/jkms.2022.37.e147.

Abstract

With the spread of coronavirus disease 2019 (COVID-19) in Korea, the number of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly increasing. A shortage of negative-pressure isolation rooms for newborns makes hospital assignment more difficult for late-pregnant women with COVID-19. Among 34 infants born to SARS-CoV-2-positive mothers, 5 (14.7%) presented with respiratory distress and 1 (2.9%) presented with feeding intolerance that required specialized care. Aerosol-generating procedures were performed in one infant. Overall outcomes of 34 infants were favorable, and no infant tested positive for SARS-CoV-2. Most infants born to SARS-CoV-2-positive mothers did not need to be quarantined in a negative-pressure isolation room, and 17 (50%) mother-infant dyads were eligible for rooming-in. If negative-pressure isolation rooms are selectively used for newborns requiring aerosol-generating procedures or newborns in respiratory distress, resource availability for lower-risk cases may improve.

Keywords: COVID-19; Disease Transmission, Infectious; Infant, Newborn; Negative-Pressure Isolation; Pregnancy; SARS-CoV-2.

MeSH terms

  • COVID-19*
  • Female
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical / prevention & control
  • Mothers
  • Pregnancy
  • Pregnancy Complications, Infectious*
  • Respiratory Distress Syndrome*
  • SARS-CoV-2