Validation of Metroticket Score in the Preoperative Period of Liver Transplantation for Hepatocellular Carcinoma

Transplant Proc. 2022 Jun;54(5):1308-1309. doi: 10.1016/j.transproceed.2022.03.012. Epub 2022 May 6.

Abstract

Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer in the world, and liver transplant (LT) is a good therapeutic option in selected cases because it treats the neoplasm and the underlying disease. Recurrence after LT is usually aggressive and has low survival; thus, an adequate selection of recipients is ideal. The new models aim to assess the individual risk of HCC recurrence in patients undergoing LT and to improve post-LT survival. In this study, our aim was to assess the applicability of the "Metroticket" score, correlating it with our rates of recurrence and survival after LT. Overall survival at 5 years in our study differed from that in Metroticket 2.0 because that study did not consider only recurrence as the cause of death; our study evaluated only patients with recurrence, so we were able to validate the score as a predictor of greater tumor aggressiveness after LT.

MeSH terms

  • Carcinoma, Hepatocellular* / pathology
  • Humans
  • Liver Neoplasms* / pathology
  • Liver Transplantation* / adverse effects
  • Neoplasm Recurrence, Local / etiology
  • Preoperative Period
  • Retrospective Studies
  • Risk Factors