Artificial intelligence-based strategies to identify patient populations and advance analysis in age-related macular degeneration clinical trials

Affiliations

• ¹ New England Eye Center, Tufts University Medical Center, Boston, MA, USA.
• ² Department of Ophthalmology, University of Washington, Seattle, WA, USA; Karalis Johnson Retina Center, Seattle, WA, USA.
• ³ Moorfields Eye Hospital & UCL Institute of Ophthalmology, London, UK.
• ⁴ Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
• ⁵ Federal University of Sao Paulo, Sao Paulo, Brazil.
• ⁶ Optos Plc, Dunfermline, Scotland, United Kingdom.
• ⁷ Department of Ophthalmology & Visual Sciences, Medical College of Wisconsin, 925 N 87th Street, Milwaukee, WI, 53226, USA.
• ⁸ Genentech, South San Francisco, CA, USA.
• ⁹ Iveric Bio, Parsippany, NJ, USA.
• ¹⁰ Carl Zeiss Meditec, Inc, Dublin, CA, USA.
• ¹¹ Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA.
• ¹² Office of the Director, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
• ¹³ Health and Medical University, Potsdam, Germany.
• ¹⁴ Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Cleveland Institute of Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
• ¹⁵ Nidek, CO. LTD, Aichi, Japan.
• ¹⁶ Doheny Eye Institute, University of California, Los Angeles, CA, USA.
• ¹⁷ Heidelberg Engineering, Heidelberg, Germany.
• ¹⁸ Department of Bioinformatics, Genentech, South San Francisco, CA, 94080, USA.
• ¹⁹ Department of Ophthalmology and Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
• ²⁰ Department of Ophthalmology, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
• ²¹ Apellis Pharmaceuticals, Waltham, MA, USA.
• ²² Doheny Eye Institute, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.
• ²³ NIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital, London, UK.
• ²⁴ Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Italy.
• ²⁵ Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore.
• ²⁶ Icare USA Inc, Raleigh, NC, USA.
• ²⁷ New England Eye Center, Tufts University Medical Center, Boston, MA, USA. Electronic address: nadiakwaheed@gmail.com.