Evaluation of two local anaesthetic sprays for the relief of post-episiotomy pain

Curr Med Res Opin. 1987;10(6):364-9. doi: 10.1185/03007998709111104.

Abstract

Aerosol formulations of lignocaine (5%) and cinchocaine (2%) were compared with a water-only placebo spray in a single-dose study in 76 primiparous patients complaining of moderate or severe post-episiotomy pain. In comparison with a water-only placebo, both local anaesthetic formulations gave significant relief when administered to the perineal wound but the lignocaine spray proved to be the more effective. The only side-effect reported was slight stinging occurring immediately after administration of the lignocaine spray in 2 cases. Serum concentrations of local anaesthetic post-administration were negligible. An interesting finding was that breast-feeding patients responded less well to this form of analgesia than patients in whom lactation had been suppressed with frusemide.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aerosols
  • Analgesia / methods*
  • Breast Feeding
  • Clinical Trials as Topic
  • Dibucaine / administration & dosage*
  • Episiotomy / adverse effects*
  • Female
  • Humans
  • Lidocaine / administration & dosage*
  • Pain, Postoperative / drug therapy*
  • Postpartum Period
  • Pregnancy
  • Random Allocation
  • Time Factors

Substances

  • Aerosols
  • Lidocaine
  • Dibucaine