Predicting Outcomes in Trauma Patients With Cirrhosis Using Model for End-Stage Liver Disease Score: A Retrospective Study

Am Surg. 2023 Jun;89(6):2383-2390. doi: 10.1177/00031348221093534. Epub 2022 May 6.

Abstract

Background: Liver cirrhosis is associated with increased mortality in trauma victims. We stratified the impact of cirrhosis on trauma mortality by Model for End-stage Liver Disease (MELD) score.

Methods: Trauma center database was accessed for patients with established diagnosis of cirrhosis presenting 2014 - 2018, matched to control patients without cirrhosis in a 2:1 ratio by age, sex, and TRISS. Primary outcome was mortality, secondary outcomes were length of stay, intensive care unit days, and ventilator dependent days.

Results: Cirrhosis was present in 182 (1.5%) trauma patients. Mortality difference between 12 (7%) deaths in cirrhosis cohort versus 14 (4%) in control was not statistically significant (p = 0.38). No difference was found in secondary outcomes. Categorization of cirrhosis severity by MELD score range (MELD 6-7, 8-10, 11-14, 15-20, 21-30) showed a 1.9 fold increase in the odds of mortality for every increase in MELD score category (OR = 1.91, p = 0.03, 95% CI = 1.08 - 3.37).

Conclusion: Mortality effects of cirrhosis in trauma patients can be estimated using MELD score.

Keywords: acute care surgery; liver; trauma; trauma acute care.

MeSH terms

  • End Stage Liver Disease* / complications
  • Humans
  • Liver Cirrhosis / complications
  • Liver Function Tests
  • Prognosis
  • Retrospective Studies
  • Severity of Illness Index