Rhodium(iii)-catalyzed C-H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles

He Li; Ye Lu; Xinxin Jin; Shuang Sun; Limei Duan; Jinghai Liu

doi:10.1039/d0ra07701a

Rhodium(iii)-catalyzed C-H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles

RSC Adv. 2020 Oct 30;10(65):39708-39711. doi: 10.1039/d0ra07701a. eCollection 2020 Oct 27.

Authors

He Li¹, Ye Lu¹, Xinxin Jin¹, Shuang Sun¹, Limei Duan¹, Jinghai Liu¹

Affiliation

¹ Inner Mongolia Key Laboratory of Carbon Nanomaterials, Nano Innovation Institute (NII), College of Chemistry and Materials Science, Inner Mongolia University for Nationalities Tongliao 028000 China jhliu2008@sinano.ac.cn duanlmxie@126.com.

Abstract

An efficient Rh(iii)-catalyzed synthesis of 2-arylindole derivatives via intermolecular C-H annulation of arylhydrazines with sulfoxonium ylides was accomplished. A variety of 2-acetyl-1-arylhydrazines with sulfoxonium ylides were converted into 2-arylindoles in satisfactory yields. Excellent selectivity and good functional group tolerance of this transformation were also observed.