Ring-opening 1,3-arylboration of arylcyclopropanes mediated by BCl3

Yuichi Kuboki; Mitsuhiro Arisawa; Kenichi Murai

doi:10.1039/d0ra08151e

Ring-opening 1,3-arylboration of arylcyclopropanes mediated by BCl₃

RSC Adv. 2020 Oct 13;10(62):37797-37799. doi: 10.1039/d0ra08151e. eCollection 2020 Oct 12.

Authors

Yuichi Kuboki¹, Mitsuhiro Arisawa¹, Kenichi Murai¹

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Osaka University 1-6 Yamada-oka Suita Osaka 565-0871 Japan murai@phs.osaka-u.ac.jp.

Abstract

Herein, we report a ring-opening 1,3-arylboration of aryl cyclopropanes using BCl₃ in the presence of arene nucleophiles. Formal 1,3-oxy arylation and 1,3-amino arylation of the arylcyclopropane via one-pot derivatization of the installed boron group were also achieved.