Risk assessment of selected pharmaceuticals on wildlife with nanomaterials based aptasensors

Sci Total Environ. 2022 Aug 25:836:155622. doi: 10.1016/j.scitotenv.2022.155622. Epub 2022 May 1.

Abstract

Pharmaceuticals have improved human and veterinary health tremendously over the years. But the implications of the presence of pharmaceuticals in the environment on terrestrial, avian, and aquatic organisms are still not fully comprehended. The bioaccumulation and biomagnifications of these chemicals through the food chain have long-term effects on the wildlife. The detection and quantification of such pharmaceutical residues in the environment is a tedious process and quicker methods are needed. Aptasensors are one such quick and reliable method for the identification of pharmaceutical residues in the wildlife. Aptasensors are a class of biosensors that work on the principles of biological recognition of elements. The aptamers are unique biological recognition elements with high specificity and affinity to various targets. Their efficiency makes them a very promising candidate for such sensitive research. In this review, the pharmaceutical threats to wildlife and their detection techniques using aptasensors have been discussed.

Keywords: Aptamers; Biosensors; Pharmaceuticals; Veterinary drugs; Wildlife toxicity.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Wild
  • Aptamers, Nucleotide* / chemistry
  • Biosensing Techniques* / methods
  • Humans
  • Nanostructures*
  • Pharmaceutical Preparations
  • Risk Assessment

Substances

  • Aptamers, Nucleotide
  • Pharmaceutical Preparations