Hard X-ray excited optical luminescence from protein-directed Au∼20 clusters

Zuoyue Liu; Kyung Oh Jung; Ryo Takahata; Masanori Sakamoto; Toshiharu Teranishi; Mamoru Fujitsuka; Guillem Pratx; Yasuko Osakada

doi:10.1039/d0ra01935f

Hard X-ray excited optical luminescence from protein-directed Au_∼20 clusters

RSC Adv. 2020 Apr 6;10(23):13824-13829. doi: 10.1039/d0ra01935f. eCollection 2020 Apr 1.

Authors

Zuoyue Liu¹, Kyung Oh Jung², Ryo Takahata³, Masanori Sakamoto³, Toshiharu Teranishi³, Mamoru Fujitsuka¹, Guillem Pratx², Yasuko Osakada^{1

4}

Affiliations

¹ The Institute of Scientific and Industrial Research (SANKEN), Osaka University Mihogaoka 8-1 Osaka 567-0047 Ibaraki Japan yosakada@sanken.osaka-u.ac.jp.
² Department of Radiation Oncology and Medical Physics, Stanford University 300 Pasteur Dr Stanford CA 94305 USA.
³ Institute for Chemical Research, Kyoto University Gokasho, Uji Kyoto 611-0011 Japan.
⁴ Institute for Advanced Co-creation Studies, Osaka University 1-1 Yamadagaoka, Suita Osaka 565-0871 Japan.

Abstract

Hard X-ray excited optical luminescence is a unique property of materials, which makes them promising for biological imaging applications. However, the preparation of biocompatible contrast agents for hard X-ray excited optical luminescence remains a considerable challenge that has, to date, not been overcome. In this study, we investigated the luminescence properties of protein-directed Au_∼20 clusters upon hard X-ray irradiation, both in solution and when embedded in films.