Seroprevalence of hepatitis E virus infection among volunteer blood donors in Central Brazil

Braz J Infect Dis. 2022 Mar-Apr;26(2):102350. doi: 10.1016/j.bjid.2022.102350. Epub 2022 Apr 26.

Abstract

A cross-sectional study was carried out in the Hematology and Hemotherapy Institute of the state of Mato Grosso do Sul (Hemosul) to evaluate the seroprevalence and risk factors of Hepatitis E Virus (HEV) exposure among volunteer blood donors in Central Brazil. Two-hundred fifty samples from the biorepository were tested for anti-HEV IgG and IgM using the Wantai HEV ELISA test. The seroprevalence of HEV exposure was 6.4% (95% CI: 3.9-10.2). Being born in another state of Brazil, mainly in the Southeast and South regions, was associated with a higher risk of HEV exposure (p < 0.001).

Keywords: Blood donors; Hepatitis E virus; Prevalence.

MeSH terms

  • Blood Donors
  • Brazil / epidemiology
  • Cross-Sectional Studies
  • Hepatitis Antibodies
  • Hepatitis E virus*
  • Hepatitis E* / epidemiology
  • Humans
  • Immunoglobulin M
  • Seroepidemiologic Studies
  • Volunteers

Substances

  • Hepatitis Antibodies
  • Immunoglobulin M