Potential efficacy of multipoint pacing in the reduction of mitral regurgitation volume: a case report

ESC Heart Fail. 2022 Aug;9(4):2724-2727. doi: 10.1002/ehf2.13944. Epub 2022 Apr 28.

Abstract

A 70-year-old woman who had cardiac sarcoidosis and severe tethering mitral regurgitation (MR) and had been implanted with a biventricular pacemaker experienced recurrent hospitalisation due to decompensated heart failure (HF). Application of MultiPoint™ pacing reduced the MR volume and maintained the symptoms under control; however, the predicted longevity of the device significantly decreased because of the very high threshold of the added pacing site. Transcatheter mitral valve repair (TMVR) using MitraClip® was performed to further diminish the severe MR, thereby enabling the switch from highly consumptive multipoint pacing (MPP) to energy-saving single-point pacing. MPP could further reduce MR compared to the conventional single-point pacing, and this could be a bridging therapy to TMVR in some patients implanted with a biventricular pacemaker. This is the first case to report that switching from conventional single-point pacing to MPP decreased the MR, to some extent, resulting in the improvement of HF symptoms.

Keywords: Heart failure; Mitral regurgitation; Multipoint pacing; Transcatheter mitral valve repair.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiac Surgical Procedures* / adverse effects
  • Female
  • Heart Failure*
  • Hospitalization
  • Humans
  • Mitral Valve Insufficiency* / diagnosis
  • Mitral Valve Insufficiency* / etiology
  • Mitral Valve Insufficiency* / surgery
  • Pacemaker, Artificial* / adverse effects