Construction of Molecular Robots from Microtubules for Programmable Swarming

Jakia Jannat Keya; Mousumi Akter; Arif Md Rashedul Kabir; Mst Rubaya Rashid; Akira Kakugo

doi:10.1007/978-1-0716-1983-4_14

Construction of Molecular Robots from Microtubules for Programmable Swarming

Methods Mol Biol. 2022:2430:219-230. doi: 10.1007/978-1-0716-1983-4_14.

Authors

Jakia Jannat Keya¹, Mousumi Akter¹, Arif Md Rashedul Kabir¹, Mst Rubaya Rashid², Akira Kakugo^{3

4}

Affiliations

¹ Faculty of Science, Hokkaido University, Sapporo, Japan.
² Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo, Japan.
³ Faculty of Science, Hokkaido University, Sapporo, Japan. kakugo@sci.hokudai.ac.jp.
⁴ Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo, Japan. kakugo@sci.hokudai.ac.jp.

PMID: 35476335
DOI: 10.1007/978-1-0716-1983-4_14

Abstract

Swarm robotics has been attracting much attention in recent years in the field of robotics. This chapter describes a methodology for the construction of molecular swarm robots through precise control of active self-assembly of microtubules (MTs). Detailed protocols are presented for the construction of molecular robots through conjugation of DNA to MTs and demonstration of swarming of the MTs. The swarming is mediated by DNA-based interaction and photoirradiation which act as processors and sensors respectively for the robots. Furthermore, the required protocols to utilize the swarming of MTs for molecular computation is also described.

Keywords: DNA Programming; Kinesin; Microtubule; Molecular robot; Photoresponsive DNA; Swarming.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computers, Molecular
DNA / genetics
Microtubules
Robotics* / methods

Substances

DNA