Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction

Bonpei Takase; Yukie Kobayashi; Natsuko Sasaki; Katsumi Hayashi; Tetsuya Hisada; Masami Sakurada; Nobuyuki Masaki; Masayoshi Nagata

doi:10.1093/omcr/omac040

Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction

Oxf Med Case Reports. 2022 Apr 19;2022(4):omac040. doi: 10.1093/omcr/omac040. eCollection 2022 Apr.

Authors

Bonpei Takase¹, Yukie Kobayashi², Natsuko Sasaki², Katsumi Hayashi², Tetsuya Hisada², Masami Sakurada³, Nobuyuki Masaki¹, Masayoshi Nagata²

Affiliations

¹ Department of Intensive Care Medicine, National Defense Medical College, Tokorozawa city, Saitama, Japan.
² Division of Cardiology, Iruma Heart Hospital, Iruma city, Saitama, Japan.
³ Division of Cardiology, Tokorozawa Heart Center, Tokorozawa city, Saitama, Japan.

Abstract

ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pain and no coronary risk factors. STEMI caused by VSA was diagnosed. Flow-mediated vasodilatation (FMD) and EndPAT tests were performed; the FMD and reactive hyperaemia index were 3.8% and 1.23, respectively. Endothelial dysfunction is the putative cause of STEMI. FMD and EndPAT tests might be useful for predicting adverse outcomes in young premenopausal women with VSA.

Publication types

Case Reports