Laboratory medicine in pandemic of COVID-19

Biochem Med (Zagreb). 2022 Jun 15;32(2):020501. doi: 10.11613/BM.2022.020501. Epub 2022 Apr 15.

Abstract

After the outbreak in China in the year 2019, severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) quickly spread around the world causing a protracted pandemic. Approximately one-third of infections appear to be asymptomatic. Symptomatic disease is characterized primarily by symptoms of respiratory tract infection of varying severity. But Coronavirus Disease 2019 (COVID-19) is much more than an acute respiratory disease because SARS-CoV-2 affects many organs inducing a vast number of symptoms such as cardiovascular, neurological, gastrointestinal, dermatological, with numerous complications. Short and long-term effects of infection, severe ones, and especially mild forms of the disease which affect a huge number of patients need to be further investigated. Laboratory medicine has a crucial role in early diagnosis of the disease, recognition of the patients who need hospital care, and close monitoring of hospitalized patients to timely identify associated clinical complications as well as follow-up of patients with long-term COVID-19.

Keywords: COVID-19; GDF-15; Guillain-Barré syndrome; infertility; interleukin-6.

MeSH terms

  • COVID-19*
  • China
  • Humans
  • Laboratories
  • Pandemics*
  • SARS-CoV-2