Endocrine Regulation on Bone by Thyroid

Siyuan Zhu; Yidan Pang; Jun Xu; Xiaoyi Chen; Changqing Zhang; Bo Wu; Junjie Gao

doi:10.3389/fendo.2022.873820

Endocrine Regulation on Bone by Thyroid

Front Endocrinol (Lausanne). 2022 Apr 5:13:873820. doi: 10.3389/fendo.2022.873820. eCollection 2022.

Authors

Siyuan Zhu¹, Yidan Pang², Jun Xu², Xiaoyi Chen³, Changqing Zhang², Bo Wu¹, Junjie Gao^{2

3}

Affiliations

¹ Department of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
² Department of Orthopaedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
³ Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China.

Abstract

Background: As an endocrine organ, the thyroid acts on the entire body by secreting a series of hormones, and bone is one of the main target organs of the thyroid.

Summary: This review highlights the roles of thyroid hormones and thyroid diseases in bone homeostasis.

Conclusion: Thyroid hormones play significant roles in the growth and development of bone, and imbalance of thyroid hormones can impair bone homeostasis.

Keywords: bone; bone homeostasis; thyroid; thyroid diseases; thyroid hormones.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Bone and Bones
Endocrine System* / physiology
Hormones
Thyroid Gland*
Thyroid Hormones / physiology

Substances

Hormones
Thyroid Hormones