Nano-Therapeutics to Treat Acne Vulgaris

Indian J Microbiol. 2022 Jun;62(2):167-174. doi: 10.1007/s12088-022-01001-4. Epub 2022 Jan 29.

Abstract

Nanotechnology is a novel approach to dermatologic treatment. Nanomaterials are materials typically defined as less than 100 nm in size. As this size approaches molecular dimensions, the chemical and physical properties vastly change due to a relative increase in surface area to volume ratio. Unique and altered properties ensue, such as carbon becoming an electrical conductant in the nano form, and glass becoming a liquid. The interaction of nanoparticles with biota likewise changes. Novel therapeutics may be possible with the use of nanomaterials. Advantages of nanoparticles include the ability to overcome microbial resistance and potentially induce immunomodulatory effects. Engineered nanomaterials or the development of nano-therapeutics with photo-induced antibacterial propensity and immunomodulatory activities has the potential to open new prospects for the treatment of ubiquitous cutaneous diseases, such as acne vulgaris.

Keywords: Acne vulgaris; Nanodermatology; Nanotechnology; Phototherapy; Propionibacterium acnes.

Publication types

  • Review