[Research progress on the relationship between liver cirrhosis and thyroid hormones]

Zhonghua Gan Zang Bing Za Zhi. 2022 Mar 20;30(3):331-334. doi: 10.3760/cma.j.cn501113-20210508-00225.
[Article in Chinese]

Abstract

There exists a complex relationship between liver and thyroid hormones. Liver plays an important role in the activation, inactivation, transportation, and metabolism of thyroid hormones. At the same time, thyroid hormones also affect hepatocytes activity and liver metabolism, such as lipid and bilirubin metabolism. Importantly, thyroid hormone levels often change abnormally in patients with liver cirrhosis. Therefore, studying the change of thyroid hormone levels in patients with liver cirrhosis has a certain clinical value for assessing the severity, prognosis, diagnosis and treatment. This paper reviews the research progress on the relationship between liver cirrhosis and thyroid hormone.

肝脏与甲状腺激素之间存在复杂关系,肝脏在甲状腺激素的激活、失活、转运和代谢中起着重要作用。同时,甲状腺激素也会影响肝细胞的活动及肝脏的新陈代谢,如脂代谢、胆红素代谢等。肝硬化患者多存在甲状腺激素水平的异常改变,研究肝硬化患者甲状腺激素水平的变化,对判断肝硬化患者病情严重程度、预后及诊疗有一定的临床价值。现就肝硬化与甲状腺激素的相关性研究进展进行综述。.

Publication types

  • Review

MeSH terms

  • Bilirubin
  • Humans
  • Liver / metabolism
  • Liver Cirrhosis* / metabolism
  • Thyroid Hormones* / metabolism

Substances

  • Thyroid Hormones
  • Bilirubin