The exploitation of accurate and robust photoelectrochemical (PEC) approaches in whole biosensing community counts on the smooth electrons transport and delicate biological design. An aptasensor using depositional rutile titanium dioxide/bismuth vanadate nanoarrays (TiO2/BiVO4 NAs) as photoanode generator and strand-displacement model as nucleic acid frame was developed for microRNA-155 (miRNA-155) detection root in original idea. Photoanode was fabricated via a three-step overlayer deposition procedure including hydrothermal method, electrodeposition and ion beam sputtering. With a sufficient dense of oriented arrays, it provided a solid substrate and fast electronic kinetics reaction during host-guest recognition. In situ yielding electron donors were integrated into the PEC system to provide the most accurate quantitative analysis. The nanoarrays-triggered PEC platform opens another potential perspective in biosensing.
Keywords: DNA strand displacement; In situ photoelectrochemical; TiO(2)/BiVO(4) nanoarrays; microRNA-155.
Copyright © 2022 Elsevier B.V. All rights reserved.