Whole-Body Vibration Promotes Skeletal Muscle Restructuring and Reduced Obesogenic Effect of MSG in Wistar Rats

Appl Biochem Biotechnol. 2022 Aug;194(8):3594-3608. doi: 10.1007/s12010-022-03923-7. Epub 2022 Apr 23.

Abstract

The negative changes of obesity to the locomotor system are a major concern in the current scenario, where obesity and metabolic syndrome are recurrent in Western societies. A physical exercise is an important tool as a way to rehabilitate obesity, highlighting whole-body vibration, as it is an easy-access modality with few restrictions. In this sense, we sought to evaluate the effect of whole-body vibration on the extensor digitorum longus muscle on a monosodium glutamate-induced obesity model. The main findings of the present study are related to the ability of the treatment with vibration to reduce the obesogenic characteristics and slow down the dyslipidemic condition of the animals. Likewise, the vibration promoted by the vibrating platform was essential in the recovery of the muscle structure, as well as the recovery of the muscle's oxidative capacity, initially compromised by obesity.

Keywords: Extensor digitorum longus; Metabolic syndrome; Morphological alterations; Obesity alterations; Physical exercise.

MeSH terms

  • Animals
  • Muscle, Skeletal / metabolism
  • Obesity / chemically induced
  • Obesity / metabolism
  • Rats
  • Rats, Wistar
  • Sodium Glutamate* / metabolism
  • Sodium Glutamate* / toxicity
  • Vibration*

Substances

  • Sodium Glutamate