Advanced heart failure and cardiac arrhythmia in a young adult survivor of childhood cancer

Vnitr Lek. 2022 Winter;68(E-1):22-26.

Abstract

The goal of this case report is to describe the young childhood cancer survivor who was treated for nonHodgkin lymphoma with chemotherapy containing anthracycline doxorubicin and who developed symptoms of serious cardiovascular damage 27 years after diagnosis of cancer. The patient is in longterm complete remission of the lymphoma. He started guideline medical therapies for chronic heart failure and had a cardioverter defibrillator implanted for primary prevention of sudden cardiac death. He is currently a candidate for heart transplantation.

Keywords: Arrhythmia; anthracyclines; heart failure; implantable cardioverter defibrillator; implantable cardioverter-defibrillator; late cardiotoxicity; treatment.

Publication types

  • Case Reports

MeSH terms

  • Arrhythmias, Cardiac / complications
  • Arrhythmias, Cardiac / therapy
  • Child
  • Death, Sudden, Cardiac / etiology
  • Death, Sudden, Cardiac / prevention & control
  • Defibrillators, Implantable* / adverse effects
  • Heart Failure* / complications
  • Heart Failure* / therapy
  • Humans
  • Male
  • Neoplasms* / complications
  • Survivors
  • Young Adult