Developing Community Resources for Nucleic Acid Structures

Helen M Berman; Catherine L Lawson; Bohdan Schneider

doi:10.3390/life12040540

Developing Community Resources for Nucleic Acid Structures

Life (Basel). 2022 Apr 6;12(4):540. doi: 10.3390/life12040540.

Authors

Helen M Berman¹, Catherine L Lawson², Bohdan Schneider³

Affiliations

¹ Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
² Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
³ Institute of Biotechnology of the Czech Academy of Sciences, 252 50 Vestec, Czech Republic.

Abstract

In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has been used to enable research. Plans for the next phase as the Nucleic Acid Knowledgebase (NAKB) are summarized.

Keywords: DNA; RNA; biological structure database; nucleic acid conformation; nucleic acid structures; validation standards.

Publication types

Review

Abstract

Publication types

Grants and funding