Antibacterial Molecules from Marine Microorganisms against Aquatic Pathogens: A Concise Review

Mar Drugs. 2022 Mar 28;20(4):230. doi: 10.3390/md20040230.

Abstract

Antibiotic resistance and residues in aquaculture are a growing concern worldwide and consequently identifying favorable antibacterial compounds against aquatic pathogenic bacteria are gained more attention. Active compounds derived from marine microorganisms have shown great promise in this area. This review is aimed to make a comprehensive survey of anti-aquatic pathogenic bacterial compounds that were produced by marine microorganisms. A total of 79 compounds have been reported, covering literature from 1997 to 2021. The compounds are included in different structural classes such as polyketides, terpenoids, nitrogen compounds and others, and some of them present the potential to be developed into agents for the treatment of aquatic pathogenic bacteria.

Keywords: antibacterial molecules; aquatic bacterial pathogens; marine microorganisms.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Aquatic Organisms* / chemistry
  • Bacteria / chemistry
  • Polyketides*
  • Terpenes / chemistry

Substances

  • Anti-Bacterial Agents
  • Polyketides
  • Terpenes