A neuropeptide regulates immunity across species

Neuron. 2022 Apr 20;110(8):1275-1277. doi: 10.1016/j.neuron.2022.03.036.

Abstract

Communication between the nervous system and immune system is important for regulating immunity in health and disease. Yu et al. (2022) show that neuropeptide Y and its homolog NPF serve as a "language" to facilitate crosstalk between these two systems across species, enabling neurons to downregulate harmful immune responses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Central Nervous System Depressants*
  • Nervous System
  • Neurons
  • Neuropeptide Y
  • Neuropeptides*

Substances

  • Central Nervous System Depressants
  • Neuropeptide Y
  • Neuropeptides