Hormonal Effects on Asthma, Rhinitis, and Eczema

J Allergy Clin Immunol Pract. 2022 Aug;10(8):2066-2073. doi: 10.1016/j.jaip.2022.04.002. Epub 2022 Apr 15.

Abstract

Hormones significantly influence the pathogenesis of asthma, rhinitis, and eczema. This review aims to summarize relevant clinical considerations for practicing allergists and immunologists. The first section reviews the effects of sex hormones: estrogen, progesterone, and testosterone. The second concerns insulin production in the context of type 1 and type 2 diabetes. The third concludes with a discussion of thyroid and adrenal pathology in relationship to asthma, rhinitis, and eczema.

Keywords: Adrenal insufficiency; Allergic; Androgens; Asthma; Atopic dermatitis; Diabetes mellitus; Eczema; Estrogen; Hypercortisolism; Hyperthyroidism; Hypothyroidism; Neuroendocrine; Testosterone.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Asthma* / etiology
  • Dermatitis, Atopic* / complications
  • Diabetes Mellitus, Type 2*
  • Eczema*
  • Humans
  • Prevalence
  • Rhinitis* / complications