Functional interplay between the Hippo pathway and heavy metals

Mol Cell Oncol. 2022 Apr 9;9(1):2061297. doi: 10.1080/23723556.2022.2061297. eCollection 2022.

Abstract

Emerging studies highlight the Hippo pathway as an important player in organ size control, tissue homeostasis, regeneration, development, and diseases, but our understanding of its roles and regulations remains incomplete. Our recent work reported a functional interplay between the Hippo pathway and heavy metals, providing new insights into this key signaling pathway.

Keywords: Hippo; LATS; MTF1; heavy metals.