Disc-like lesions in the intestinal tract after renal transplantation

Arjan J Kwakernaak; Rob W van der Pluijm; Neelke C van der Weerd; Lianne Koens; Wytske M Westra; Krisztina B Gecse; Ankie Kleinjan

doi:10.1002/ccr3.5645

Disc-like lesions in the intestinal tract after renal transplantation

Clin Case Rep. 2022 Apr 12;10(4):e05645. doi: 10.1002/ccr3.5645. eCollection 2022 Apr.

Authors

Arjan J Kwakernaak¹, Rob W van der Pluijm², Neelke C van der Weerd³, Lianne Koens⁴, Wytske M Westra⁵, Krisztina B Gecse⁵, Ankie Kleinjan⁶

Affiliations

¹ Department of Internal Medicine Division of Nephrology Department of Rheumatology and Clinical Immunology Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Rheumatology and Immunology Center Amsterdam The Netherlands.
² Department of Internal Medicine Division of Infectious Diseases Amsterdam University Medical Centers, University of Amsterdam Amsterdam The Netherlands.
³ Department of Internal Medicine Division of Nephrology Amsterdam University Medical Centers, University of Amsterdam Amsterdam The Netherlands.
⁴ Department of Pathology Amsterdam University Medical Centers, University of Amsterdam Amsterdam The Netherlands.
⁵ Department of Gastroenterology and Hepatology Amsterdam University Medical Centers, University of Amsterdam Amsterdam The Netherlands.
⁶ Department of Internal Medicine Division of Haematology Rivierenland Hospital Tiel The Netherlands.

Abstract

We report a case of intestinal lesions in a patient with a history of lupus nephritis and renal transplantation. Biopsy revealed an EBV-driven post-transplant lymphoproliferative disease (PTLD). An EBV-driven PTLD is a major complication after renal transplantation and is an important differential diagnostic consideration in the follow-up of renal transplant recipients.

Keywords: EBV; PTLD; immunosuppression; lymphoma; renal transplantation.