Organochlorine pesticide residue in Chinese herbal medicine

Mei-Yin Chien; Chih-Min Yang; Chao-Hsiang Chen

doi:10.1584/jpestics.D21-052

Organochlorine pesticide residue in Chinese herbal medicine

J Pestic Sci. 2022 Feb 20;47(1):30-34. doi: 10.1584/jpestics.D21-052.

Authors

Mei-Yin Chien¹, Chih-Min Yang¹, Chao-Hsiang Chen^{1

2}

Affiliations

¹ Ko Da Pharmaceutical Co. Ltd., No. 20-1, Gongye 3rd Rd., Pingzhen Dist., Taoyuan city 324, Taiwan R.O.C.
² Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan R.O.C.

Abstract

Over ten-year routine inspection results on organochlorine pesticide (OCP) residue were summarized, OCPs residues, including BHC isomers (α, β, γ, and δ-BHC), DDT analogs (p,p'-DDD, p,p'-DDE, o,p'-DDT, and p,p'-DDT), and pentachloronitrobenzene (PCNB) and its metabolites (pentachloroaniline and methyl pentachlorophenyl sulfide (MPCPS)), in 1,665 samples for 37 types of Chinese herbal medicine (CHM) using the QuEChERS method coupled with the GC-ECD. Based on the maximal residue levels for OCPs set by Asian pharmacopeias, PCNB contamination in Ginseng radix as well as the total DDT and PCNB contamination in Panacis quinquefolii radix are of concern. OCP residues in different parts of Panax ginseng were also compared. The total BHC residue in leaf and fibrous root, as well as the total DDT and PCNB residue in all parts, exceeded MRL of 0.1 mg/kg. Overall, this study provided meaningful results about OCP residue in CHM for pharmaceutical industries and consumers.

Keywords: Chinese herbal medicine; Ginseng radix; Panacis quinquefolii radix; organochlorine pesticides residue.

© Pesticide Science Society of Japan 2022. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License (https://creativecommons.org/licenses/by-nc-nd/4.0/).