Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events

Nat Commun. 2022 Apr 12;13(1):1956. doi: 10.1038/s41467-022-29522-y.

Abstract

The emergence of highly transmissible SARS-CoV-2 variants has created a need to reassess the risk posed by increasing social contacts as countries resume pre-pandemic activities, particularly in the context of resuming large-scale events over multiple days. To examine how social contacts formed in different activity settings influences interventions required to control Delta variant outbreaks, we collected high-resolution data on contacts among passengers and crew on cruise ships and combined the data with network transmission models. We found passengers had a median of 20 (IQR 10-36) unique close contacts per day, and over 60% of their contact episodes were made in dining or sports areas where mask wearing is typically limited. In simulated outbreaks, we found that vaccination coverage and rapid antigen tests had a larger effect than mask mandates alone, indicating the importance of combined interventions against Delta to reduce event risk in the vaccine era.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • Disease Outbreaks / prevention & control
  • Humans
  • SARS-CoV-2*
  • Ships

Supplementary concepts

  • SARS-CoV-2 variants