Characterizing systematic challenges in sample size determination for sepsis trials
Intensive Care Med
.
2022 Jun;48(6):750-752.
doi: 10.1007/s00134-022-06691-4.
Epub 2022 Apr 12.
Authors
Alexandre Tran
1
2
3
,
Shannon M Fernando
4
5
,
Bram Rochwerg
6
7
,
Christopher W Seymour
8
9
10
,
Deborah J Cook
6
7
Affiliations
1
Department of Surgery, University of Ottawa, Ottawa, Canada. aletran@toh.ca.
2
School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada. aletran@toh.ca.
3
Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, Canada. aletran@toh.ca.
4
Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, Canada.
5
Department of Emergency Medicine, University of Ottawa, Ottawa, Canada.
6
Department of Medicine, McMaster University, Hamilton, Canada.
7
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
8
Department of Critical Care, University of Pittsburgh, Pittsburgh, USA.
9
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, USA.
10
Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Pittsburgh, USA.
PMID:
35412128
PMCID:
PMC9773100
DOI:
10.1007/s00134-022-06691-4
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
Hospital Mortality
Humans
Sample Size
Sepsis* / therapy
Grants and funding
R01 HL164835/HL/NHLBI NIH HHS/United States
R21 GM144851/GM/NIGMS NIH HHS/United States
R35 GM119519/GM/NIGMS NIH HHS/United States