Highly catalysis MOFCe supported Ag nanoclusters coupled with specific aptamer for SERS quantitative assay of trace dopamine

Jinling Shi; Jingjing Li; Aihui Liang; Zhiliang Jiang

doi:10.1016/j.talanta.2022.123468

Highly catalysis MOF_Ce supported Ag nanoclusters coupled with specific aptamer for SERS quantitative assay of trace dopamine

Talanta. 2022 Aug 1:245:123468. doi: 10.1016/j.talanta.2022.123468. Epub 2022 Apr 6.

Authors

Jinling Shi¹, Jingjing Li¹, Aihui Liang², Zhiliang Jiang³

Affiliations

¹ Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin, 541004, China.
² Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin, 541004, China. Electronic address: ahliang2008@163.com.
³ Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin, 541004, China. Electronic address: zljiang@mailbox.gxnu.edu.cn.

PMID: 35405447
DOI: 10.1016/j.talanta.2022.123468

Abstract

A cerium metal organic framework-loaded silver nanocluster (MOF_CeAgNC) is synthesized by a facile stirring procedure with trimesic acid, cerium nitrate, silver nitrate and NaBH₄, which exhibites strong catalytic activity in the indicated reaction of HAuCl₄-sodium lactate (SL). MOF_CeAgNC can sensitively detect dopamine (DA) by surface-enhanced Raman scattering (SERS) and resonance Rayleigh scattering (RRS) techniques with a detection concentration range of 0.01-0.25 nmol/L and a detection limit of 0.008 nmol/L. Based on the specific binding of aptamer (Apt)-DA and the catalytic amplification strategy of MOF_CeAgNC on HAuCl₄-SL, a sensitive and convenient DA platform for dual-mode detection of SERS and RRS is constructed. In addition, the platform is successfully applied to detect DA in human serum with satisfactory recoveries (95.7-102%).

Keywords: Apt; Dopamin; MOF-Loaded silver nanoclusters; Nanocatalysis; SERS quantitative Analysis.

MeSH terms

Catalysis
Dopamine
Gold*
Humans
Metal Nanoparticles*
Oligonucleotides
Spectrum Analysis, Raman / methods

Substances

Oligonucleotides
Gold
Dopamine