Superficial Thrombophlebitis of the Penis following AstraZeneca ChAdOx1-S Vaccination: A Rare Venous Thromboembolic Complication

Joshua Winston; Kale Munien

doi:10.12890/2022_003258

Superficial Thrombophlebitis of the Penis following AstraZeneca ChAdOx1-S Vaccination: A Rare Venous Thromboembolic Complication

Eur J Case Rep Intern Med. 2022 Mar 23;9(3):003258. doi: 10.12890/2022_003258. eCollection 2022.

Authors

Joshua Winston¹, Kale Munien¹

Affiliation

¹ Urology Department, Royal Hobart Hospital, Hobart, Tasmania, Australia.

Abstract

Penile Mondor's disease is a rare condition characterised by superficial thrombophlebitis of the penis which is usually self-limiting. The cause is often unknown. The AstraZeneca ChAdOx1-S vaccine has been found to cause a hypercoagulable state, which is well documented. This case report describes a man who presented with Mondor's disease following ChAdOx1-S vaccination with no other risk factors.

Learning points: This is the first documented case of penile thrombophlebitis following ChAdOx1-S vaccination.We highlight a rare presentation of an uncommon condition.Clinicians should be aware of the clotting risks associated with ChAdOx1-S vaccination.

Keywords: AstraZeneca; COVID-19; Mondor’s disease; penile pain; thrombophlebitis.