A Case of Secretory Carcinoma in a Patient With a History of Contralateral Medullary Carcinoma

Rita Stefanucci; Domiziana Santucci; Silvia Maria Rossi; Matteo Sammarra; Eliodoro Faiella; Ermanno Cordelli; Vittorio Altomare; Rosario Francesco Grasso; Bruno Beomonte Zobel

doi:10.21873/cdp.10081

A Case of Secretory Carcinoma in a Patient With a History of Contralateral Medullary Carcinoma

Cancer Diagn Progn. 2022 Jan 3;2(1):87-92. doi: 10.21873/cdp.10081. eCollection 2022 Jan-Feb.

Authors

Rita Stefanucci¹, Domiziana Santucci¹, Silvia Maria Rossi², Matteo Sammarra¹, Eliodoro Faiella¹, Ermanno Cordelli³, Vittorio Altomare⁴, Rosario Francesco Grasso¹, Bruno Beomonte Zobel¹

Affiliations

¹ Radiology Department, Policlinico Campus Bio-Medico di Roma, Rome, Italy.
² Human Pathology Department, Policlinico Campus Bio-Medico di Roma, Rome, Italy.
³ Computer Science and Bioinformatics Laboratory, Integrated Research Centre, Campus Bio-Medico University, Rome, Italy.
⁴ Breast Surgery Department, Policlinico Campus Bio-Medico di Roma, Rome, Italy.

Abstract

Background: Secretory and medullary carcinomas of the breast are rare subtypes of infiltrating ductal carcinoma. The different histological behavior of medullary and secretory carcinomas is correlated with different imaging features on mammography, ultrasound, and magnetic resonance imaging.

Case report: We report the case of a Caucasian woman in which both subtypes of tumors were diagnosed in an 8-year time interval and evaluate, in antithesis, histopathological and imaging aspects of medullary and secretory carcinoma.

Conclusion: To our knowledge, this is the first case reported in literature of secretory carcinoma with a complete imaging tumor evaluation in a patient with a previous contralateral medullary cancer.

Keywords: Secretory carcinoma; anatomical pathology; diagnostic imaging; medullary carcinoma.

Publication types

Case Reports