Exploring linkages between drought and HIV treatment adherence in Africa: a systematic review

Kingsley Stephen Orievulu; Sonja Ayeb-Karlsson; Sthembile Ngema; Kathy Baisley; Frank Tanser; Nothando Ngwenya; Janet Seeley; Willem Hanekom; Kobus Herbst; Dominic Kniveton; Collins C Iwuji

doi:10.1016/S2542-5196(22)00016-X

Exploring linkages between drought and HIV treatment adherence in Africa: a systematic review

Lancet Planet Health. 2022 Apr;6(4):e359-e370. doi: 10.1016/S2542-5196(22)00016-X.

Authors

Affiliations

¹ Africa Health Research Institute, KwaZulu-Natal, South Africa; Centre for Africa-China Studies, University of Johannesburg, Johannesburg, South Africa; Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, UK.
² Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, UK; United Nations University Institute for Environment and Human Security, Bonn, Germany; Institute for Risk and Disaster Reduction, University College London, London, UK; School of Global Studies, University of Sussex, Brighton, UK.
³ Africa Health Research Institute, KwaZulu-Natal, South Africa.
⁴ Africa Health Research Institute, KwaZulu-Natal, South Africa; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
⁵ Africa Health Research Institute, KwaZulu-Natal, South Africa; Lincoln Institute for Health, University of Lincoln, Lincoln, UK.
⁶ Africa Health Research Institute, KwaZulu-Natal, South Africa; School of Nursing and Public Health, University of KwaZulu Natal, Durban, South Africa.
⁷ Africa Health Research Institute, KwaZulu-Natal, South Africa; Global Health and Development Department, London School of Hygiene & Tropical Medicine, London, UK.
⁸ Africa Health Research Institute, KwaZulu-Natal, South Africa; Division of Infection and Immunity, University College London, London, UK.
⁹ Africa Health Research Institute, KwaZulu-Natal, South Africa; DSI-MRC South African Population Research Infrastructure Network, Durban, South Africa.
¹⁰ School of Global Studies, University of Sussex, Brighton, UK.
¹¹ Africa Health Research Institute, KwaZulu-Natal, South Africa; Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, UK. Electronic address: c.iwuji@bsms.ac.uk.

Abstract

Climate change is directly and indirectly linked to human health, including through access to treatment and care. Our systematic review presents a systems understanding of the nexus between drought and antiretroviral therapy (ART) adherence in HIV-positive individuals in the African setting. Narrative synthesis of 111 studies retrieved from Web of Science, PubMed/MEDLINE, and PsycINFO suggests that livelihoods and economic conditions, comorbidities and ART regimens, human mobility, and psychobehavioural dispositions and support systems interact in complex ways in the drought-ART adherence nexus in Africa. Economic and livelihood-related challenges appear to impose the strongest impact on human interactions, actions, and systems that culminate in non-adherence. Indeed, the complex pathways identified by our systems approach emphasise the need for more integrated research approaches to understanding this phenomenon and developing interventions.

Publication types

Review
Systematic Review
Research Support, Non-U.S. Gov't

MeSH terms

Africa
Droughts*
HIV Infections* / drug therapy
HIV Infections* / epidemiology
Humans
Medication Adherence
Treatment Adherence and Compliance

Abstract

Publication types

MeSH terms

Grants and funding