Identification of the novel HLA-DPB1*1289:01 allele by next-generation sequencing

HLA. 2022 Aug;100(2):188-189. doi: 10.1111/tan.14629. Epub 2022 Apr 21.

Authors

Xiaojing Wang¹, Jiying Wang¹, Yan Zhang¹, Qinghua Li¹

Affiliation

¹ Department of Pathology and Lab Medicine, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

PMID: 35395146
DOI: 10.1111/tan.14629

Abstract

HLA-DPB1*1289:01 differs from HLA-DPB1*05:01:01:01 by one nucleotide substitution in codon 194 in exon 4.

Keywords: HLA; new allele; sequence-based typing.

© 2022 John Wiley & Sons A/S . Published by John Wiley & Sons Ltd.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Base Sequence
HLA-DP beta-Chains / genetics
High-Throughput Nucleotide Sequencing*
Humans

Substances

HLA-DP beta-Chains
HLA-DPB1 antigen