Design, Development and Validation of a Knee Brace to Standardize the US Imaging Evaluation of Knee Osteoarthritis

IEEE J Transl Eng Health Med. 2021 Dec 22:10:1800308. doi: 10.1109/JTEHM.2021.3137628. eCollection 2022.

Abstract

Objective: A repeatable and reliable follow-up of knee injuries would be desirable to prevent delayed diagnosis and to monitor the efficacy of the applied treatment over time. Ultrasound (US) techniques are an attractive option to this purpose, since they are safe, low-cost and non-invasive. However, its use in the clinical practice is limited by the high dependency on the operator's experience. Hence, the objective of this study is to provide a standardization of the US image acquisition process for knee osteoarthritis (OA) allowing an extended clinical use of US technologies in this domain.

Methods: Clinical specifications were provided by expert musculoskeletal radiologists thus identifying the subject poses and the US probe positions needed to evaluate the cartilage structure, signs of synovitis and joint effusion. Such considerations were used to derive the technical requirements needed for the development of a wearable brace equipped with specific openings to guide the correct placement of the probe. The feasibility of the developed wearable brace was tested on three healthy volunteers, which were asked to acquire informative US images, similar to the reference images performed by the musculoskeletal radiologist.

Results: Thanks to the knee brace, the untrained subjects were able to self-acquire informative B-mode images comparable to the corresponding images acquired by an expert clinician.

Discussion/conclusion: The use of a knee brace intended for knee OA US diagnosis demonstrated the possibility to standardize the acquisition protocol and make its application achievable also for untrained subjects, representing a key step toward tele-ultrasonography.

Keywords: Acquisition standardization; osteoarthritis; tele-ultrasonography; ultrasound imaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Braces
  • Humans
  • Knee Joint / diagnostic imaging
  • Osteoarthritis, Knee* / diagnostic imaging
  • Synovitis*
  • Ultrasonography

Grants and funding

This work was supported by the European Union’s Horizon 2020 Research and Innovation Program through the Project Advanced nanocomposite MAterIals fOr in situ treatment and ultRAsound-mediated management of osteoarthritis (ADMAIORA) under Grant 814413.