Pharmacology and Ethnomedicinal Potential of Selected Plants Species from Apiaceae (Umbelliferae)

Comb Chem High Throughput Screen. 2023;26(2):256-288. doi: 10.2174/1386207325666220406110404.

Abstract

Background: The Apiaceae or Umbelliferae is one of the largest families in terms of species representation in the plant kingdom. It is also a prominent family in the field of phytochemicals and pharmacology. The family is also quite prominent in the production of spices and condiments and food supplements in nutrition, aside from the potential of species in the family to induce apoptotic, antimicrobial, antitumor, and hepatoprotective activities.

Objective: This work presents a detailed structural elucidation and functional aspects of phytochemicals from the Apiaceae or Umbelliferae family.

Methods: Furthermore, the application of members of this family in traditional and modern pharmacology is emphasized. This review also highlights the linkage of phytochemicals used in the conventional system of medication for the development of novel therapeutics through a chain of pre-clinical and clinical trials.

Conclusion: This study may represent a valuable step ahead in the clinical development of natural drugs for curing several ailments, including respiratory and virus-related diseases.

Keywords: Apiaceae; Umbelliferae; anti-viral; clinical trials; functional foods; pharmacology.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apiaceae*
  • Humans
  • Medicine, Traditional
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology
  • Plants

Substances

  • Phytochemicals